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The Oral
Health Services Research Centre is located in a purpose-built facility
providing optimum clinical and laboratory conditions together with well
equipped conference and research services.
The centre
has three complementary facets:
- It
is a clinical research testing facility providing services for
the international oral healthcare industry.
- It
is a health and health services research centre which holds peer
reviewed research grants and commissioned research contracts nationally
and internationally (WHO collaborating centre for Health Services
Research).
- It
is a postgraduate research and teaching centre supporting students
in epidemiology, health services research and related disciplines.
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It
was established in 1983 in response to growing demands for Oral
Health Services Research projects from health agencies in Ireland
and overseas, seeking appropriate policy information for the proper
planning of dental services.
The
Oral Health Services Research Centre has conducted clinical trials
of oral health care products for industry since 1994, with over
20 studies conducted to date. Subjects are recruited from the local
population, with up to 400 subjects being randomised per study.
Prior
to commencement, all clinical trials have the approval of a properly
constituted local Ethics Committee and of the regulatory authority
(Irish Medicines Board).
A full
service is available, including trial design, protocol writing,
clearance with Ethics Committee and Irish Medicines Board, recruitment
and screening of volunteers, stratification procedures, product
dispensing and reconciliation, impartial interviewing techniques,
validation procedures, microbiological measurements, biochemical
tests, quality control, statistical analysis and report writing.
All studies are performed in accordance with Good Clinical Practice
guidelines.
An
in-house clinical trials examiner is available on site. She has
been trained (and calibrated where appropriate) in the following
standardised indices / examination techniques:
- Caries:
Backer-Dirks, Bennie, FOTI, Quantitative Laser Fluorescence, x-ray
- Plaque:
Turesky Modification of the Quigley Hein Index, Rustogi Modification
of Navy Index
- Gingivitis:
Löe and Silness, MGI, Ainamo and Bay Gingival Bleeding Index
- Enamel
opacities: Thylstrup-and Fejerskov Index, Developmental Defects
of Enamel Index, Quantitative Laser Fluorescence
- Stain:
Lobene Index, McPherson Modification of Lobene Index
- Sensitivity:
Pressure (Yeaple probe), thermal (water at 5oC) and
evaporative (air blast) stimuli.
There
is a well-equipped laboratory used mainly for plaque pH studies
and fluoride analysis of oral health care products, foods, beverages,
body fluids and body tissues.
The
Centre works closely with the Health Services Executive (HSE) Dental
Service.
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| Profile
of the OHSRC |
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Director
Professor Helen P. Whelton, BDS, PhD, MDPH, MFPH.
Professor
Emeritus
Denis M. O'Mullane, BDS, PhD, FDSRCSEd, FFDRCSI
Projects
Manager
Maria Tobin, RGN, SCM, BSc Hons
Office
Manager
Susan O’Donovan, Dip Business Studies & Tourism,
Dip Prof Sec Skills
Health
Services Research Fellows
Michael Cronin, MSc
Deirdre Browne, BDS
Researchers
Paul Beirne, BDS, MDPH, PhD
Evelyn Crowley, BDS, MSc, DDPHRCS
Rose Kingston, BDS
Noel Woods, BA (Econ and Computer Sci), MA (Health Econ)
Edel Flannery, BSc (Mathematical Sci & Computing)
Tara Crowley, BA Hons (Applied Psychology & Sociology)
Virginia Kelleher, MA (Econ)
Research
Assistants
Helena Guiney, BA (Economics & Maths), MA (Economics),
MSc (Multimedia Technology)
Laboratory
Technician
Eileen MacSweeney, Nat Dip Appl Biol, Nat Cert Sc, Part
Dip Chem Tech
Clinical
Trials Co-ordinator
Maura Gallagher, RGN, SCM
Senior
Executive Assistant
Theresa O’Mahony, DSA
Executive
Assistants
Ita Rattray
Jennifer Leyden
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It has directed
national surveys on the oral health of both children and adults and also
carried out surveys for regional health authorities in the Republic of
Ireland and Northern Ireland. Currently, staff are engaged in directing
and analysing National oral health surveys of adults, children, children
with special needs, intellectually disabled adults and the elderly in
residential care. The team is also reviewing aspects of the HSE dental
services and analysing patterns of uptake of general dental practitioner
services by medical cardholders.
Full-time
research fellows and graduate students are engaged in research on behalf
of national funding agencies such as the Health Research Board (HRB).
The OHSRC has recently been funded by the HRB to conduct two major studies
entitled "The Benefits and Risks of Fluoride on the Island of Ireland"
and "Developing evidence-based clinical practice guidelines for the
health board dental services in Ireland".
The Centre
is also active in EU projects and was a participant in the AIM (Advances
in Informatics in Medicine) programme. The Oral Health Services Research
Centre was the co-ordinating partner for two projects under the EU third
and fourth Research and Technological Development Programmes, and a collaborating
partner in a further project under the EU Fifth Framework Programme. The
centre participates in an international fluoride research programme funded
by the NIH.
The Centre
has an international profile and in 1986 was designated a WHO Collaborating
Centre for Oral Health Services Research. This designation is periodically
renewed, most recently in March 2003 for a further 4-year period to March
2007. In this capacity the OHSRC provides data for the WHO global data
bank and has participated in various projects worldwide such as a feasibility
study for water fluoridation in Saudi Arabia and the writing of the WHO
document "Fluorides and Oral Health" (1994).
The centre
provides support for international researchers supporting the development
of dental public health overseas.
Research
interests of the Centre include:
- design,
conduct and analysis of clinical trials
- caries
prediction
- root
caries
- saliva
- fluoride
ingestion and absorption
- enamel
fluorosis
- chewing
gum usage
- oral
epidemiology
- use
of large oral health care payment databases to inform system design
and development
- cost
effectiveness of various oral health strategies
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The Centre
has strong links with the Departments of Statistics, Economics, Chemistry,
Microbiology, Applied Social Studies, Psychology, Computer Science and
the Computer Centre whose staff have worked on collaborative projects,
and of course with the other departments within the Dental School.
Many of the
professional staff in the Centre contribute to the teaching of Dental
Public Health at both undergraduate and postgraduate level in the Dental
School. The centre hosts postgraduate students at Masters and PhD level
in epidemiology and disciplines relevant to dental public health. It hosts
the taught Masters programme in Dental Public Health in University College
Cork.
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